Open Full Report. 2016 Sep;185(3):361-71. doi: 10.1111/cei.12803. Vineet Gupta is a resident of FL. J. Clin. Integrin CD11b agonism suppresses tumor growth and promotes survival in mouse models of cancer. Significance Our study highlights for the first time that that the O-GlcNAc transferase dependent SOX2 glycosylation determines self-renewal in pancreatic cancer which is responsible for tumor initiation. 2020 Oct 19;21(20):7716. doi: 10.3390/ijms21207716. Dr. SB is a consultant with Minneamrita Therapeutics LLC and this relationship is managed by University of Miami. View Vineet Gupta’s professional profile on LinkedIn. Here we report that, unexpectedly, integrin CD11b does not regulate myeloid cell recruitment to tumors but instead controls myeloid cell polarization and tumor growth. ... FL 33014 is the current address for Vineet. The cities are Hialeah, Miami, Oldsmar, Palm Harbor, Palmetto Bay, Pembroke Pines, Pinellas Park, Plantation, and Wesley Chapel. In contrast, inhibition of CD11b prevents Let7a expression and induces cMyc expression, leading to immune suppressive macrophage polarization, vascular maturation, and accelerated tumor growth. 2013;19:1423–1437. Yao X, Dong G, Zhu Y, Yan F, Zhang H, Ma Q, Fu X, Li X, Zhang Q, Zhang J, Shi H, Ning Z, Dai J, Li Z, Li C, Wang B, Ming J, Yang Y, Hong F, Meng X, Xiong H, Si C. Front Immunol. HHS Yao X, Dong G, Zhu Y, Yan F, Zhang H, Dai J, Li X, Xiong H, Si C. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. Pharmacological activation of CD11b with a small molecule agonist, Leukadherin 1 (LA1), promotes pro-inflammatory macrophage polarization and suppresses tumor growth in animal models of murine and human cancer. Conflict of interest University of Minnesota has a patent for Minnelide, which has been licensed to Minneamrita Therapeutics, LLC. Transcription factor SOX2 maintains a critical balance between differentiation and “stemness” and is thus tightly regulated within a cell. Conflict of interest University of Minnesota has a patent for Minnelide, which has been licensed to Minneamrita Therapeutics, LLC. Looking for Vineet Gupta? Vineet Gupta of the University of Miami in the U.S. will develop a computational model to identify new DNA sequences in the Tuberculosis bacterium that can be used as biomarkers, and then employ zinc-finger tags to detect the identified DNA sequence in a diagnostic test. 2018. Lookup the home address and phone and other contact details for this person. NIH Vineet Gupta, PhD is an Assistant Professor in Medicine in the Division of Nephrology and Hypertension, Department of Medicine at the Miller School of Medicine, University of Miami. Microenvironmental regulation of tumor progression and metastasis. Invest. eCollection 2020. Vineet Gupta in New York We found 15 results for Vineet Gupta in Brooklyn, Buffalo, and 20 other New York cities. 41 year old . -, Gabrilovich DI. These authors contributed equally: Michael C. Schmid, Samia Q. Khan, Megan M. Kaneda, Vineet Gupta, Judith A. Varner. The third result is Vineet Gupta age --in Miami, FL in the Shenandoah neighborhood. Pancreatic cancer is among the 3rd leading cause of cancer related deaths in the United States along with a 5-year survival rate of 7%. Vineet Gupta is a person living in Miami lakes, Florida. Jhansen Reinoso is a resident of Hialeah. Res. (Page 3) Nikita S Sharma, Vineet K Gupta, Patricia Dauer, Kousik Kesh, Roey Hadad, Bhuwan Giri, ... University of Miami for their help with the RNA seq transcriptomics study. Vineet Gupta is the Founder and CEO of 149 Bio. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. Please enable it to take advantage of the complete set of features! a Relative mRNA expression of pro-inflammatory…, Macrophage microRNA let-7a is required…, Macrophage microRNA let-7a is required for tumor growth suppression. Location - Miami lakes, Florida. CD11b Signaling Prevents Chondrocyte Mineralization and Attenuates the Severity of Osteoarthritis. The authors would also like to acknowledge Oncogenomics Core at the Sylvester Cancer Center, University of Miami for their help with the RNA seq transcriptomics study. Financial Support This study was funded by NIH grants R01-CA170946 and R01-CA124723 (to AKS); NIH grant R01-CA184274 (to SB); Katherine and Robert Goodale foundation support (to AKS), Minneamrita Therapeutics LLC (to AKS). 90 records for Vineet Gupta. a CD31, Desmin, NG2, Smooth muscle…, CD11b promotes miR- Let7a mediated immune stimulation. doi: 10.1097/PPO.0000000000000132. R01 CA083133/CA/NCI NIH HHS/United States, R01 CA167426/CA/NCI NIH HHS/United States, P30 CA023100/CA/NCI NIH HHS/United States, K99 HL112962/HL/NHLBI NIH HHS/United States, Quail DF, Joyce JA. USA.gov. Cancer J. Our study highlights for the first time that that the O-GlcNAc transferase dependent SOX2 glycosylation has a profound effect on the transcriptional activity of SOX2 and is instrumental in determining self-renewal in pancreatic cancer. of Surgery, University of Miami Miami, Florida 370 connections See this image and copyright information in PMC. -.  |  a – f Relative mRNA expression of…, CD11b suppresses PDGF-BB-dependent neovascularization and…, CD11b suppresses PDGF-BB-dependent neovascularization and tumor growth. Vineet Gupta; People Search Results for Vineet Gupta Profile; Phone; Address; Email; Birthday; We found 97 people that match in the United States. Int Immunopharmacol. In cancer, SOX2 is aberrantly “turned-on” leading to activation of self-renewal pathways in cancer. Whitepages people search is the most trusted directory. NOTE: Your email address is requested solely to identify you as the sender of this article. Vineet is a successful entrepreneur and has taken two startups from concept to exit. The expected price of renting a two bedrooms in the 33014 zip code is $1,730/month. -, Schmid MC, Varner JA. doi: 10.1016/j.immuni.2020.07.008. Vineet Kumar Gupta has lived in Miami, FL, in zip codes 33145 and 33156; Minneapolis, MN 55414 . Phone - (305) 620-2006 Click To Reveal. Thank you for your interest in spreading the word about bioRxiv. They have also lived in Minneapolis, MN and Pinecrest, FL. Nat. The cities are Brampton ON, Centreville VA, Coral Springs FL, Dallas TX, Glenview IL, Katy TX, Los Angeles CA, Louisville KY, Miami FL, Mississauga ON, Palm Harbor FL, Pembroke Pines FL, Pinellas Park FL, Plantation FL, Toronto ON, Upper Saddle River NJ, and … Shock. View phone numbers, addresses, public records, background check reports and possible arrest records for Vineet Gupta in Florida (FL). Vineet has 8 jobs listed on their profile. Find Vineet Gupta's phone number, address, and email on Spokeo, the leading people search directory for contact information and public records. TRADE ONE Click To Reveal. Explore Vineet Gupta's magazine "Smart City", followed by 752 people on Flipboard. MiRNA-Mediated Macrophage Polarization and its Potential Role in the Regulation of Inflammatory Response. Check Reputation Score for Vineet Gupta in Pembroke Pines, FL - View Criminal & Court Records | Photos | Address, Emails & Phone Number | Personal Review | $150 - … UHealth is now offering COVID-19 vaccine appointments to our patients age 65 and older with CDC approved risk criteria.We are contacting all eligible patients to … Select this result to view Vineet Gupta's … See Vineet's age, contact number, house address, email address, public records & run a background check. 2020 Oct 14;9(10):giaa109. About Vineet Gupta. 2020 Sep 14;11(1):4591. doi: 10.1038/s41467-020-18245-7. 2012;4:14. doi: 10.1186/2045-824X-4-14. We further showed that mutation of this site (S246A) prevents the modification of Sox2 and its downstream activity. Immunity. Epub 2020 Aug 7. Nikita S. Sharma, Vineet K. Gupta, Roey Hadad, Bhuwan Giri, Anthony Ferrantella, Vikas Dudeja, Ashok K. Saluja and Sulagna Banerjee Cancer Immunol Res April 1 2020 (8) (4 Supplement) A59; DOI: 10.1158/2326-6074.TUMIMM18-A59 These studies identify CD11b as negative regulator of immune suppression and a target for cancer immune therapy. 2018 Nov;34(11):961-968. Dr. ‪Professor of Medicine, Rush University Medical Center‬ - ‪Cited by 3,630‬ - ‪drug discovery‬ - ‪inflammation‬ - ‪integrin‬ - ‪kidney disease‬ Int J Mol Sci. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. doi: 10.1172/JCI59643. eCollection 2019. CD11b ligation promotes pro-inflammatory macrophage signaling. 2013 Dec;17(4):1185-97. doi: 10.1016/j.intimp.2013.11.010. The complement receptor 3 (CD11b/CD18) agonist Leukadherin-1 suppresses human innate inflammatory signalling. The remaining authors declare no conflict of interest. He is also The Charles Weaver Chair for Cancer Research Professor and Vice Chair for Innovation in the Department of Internal Medicine at Rush University Medical Center, Chicago, IL. LinkedIn is the world’s largest business network, helping professionals like Vineet Gupta discover inside connections to recommended job candidates, industry experts, and business partners.  |  In the current study, we show for the first time that in pancreatic cancer, Sox2 is modified by addition of O-GlcNAc moiety, catalyzed by OGT (O-GlcNAc Transferase) at S246. Clipboard, Search History, and several other advanced features are temporarily unavailable. AKS is the co-founder and the Chief Scientific Officer of this company. We found records in 27 states. a , b Endothelial…, Integrin CD11b agonism suppresses tumor growth and promotes survival in mouse models of…, NLM My post-doctoral training in Biomedical Research and Structural Biology was at the Rockefeller University in New York City and at Massachusetts General Hospital, Harvard Medical School. Norristown, Pennsylvania. 6 Drug Discovery Center, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, 60612, USA. Roberts AL, Fürnrohr BG, Vyse TJ, Rhodes B. Clin Exp Immunol. FREE Background Report. Vineet Gupta has lived in Norristown, PA 19403 . Vineet Gupta 2 & Judith A. Varner1,3 ... Miami, FL 33136, USA. Phone Number 2012;122:787–795. Location of This Business 4960 NW 165th St Unit B20, Miami Lakes, FL 33014-6322 Email this Business Cell. 2020 Aug 18;53(2):290-302.e6. 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